Tacrocord 0.5 mg Tacrocord 0.5 mg is an oral immunosuppressive medicine containing tacrolimus 0.5 mg. It works by reducing certain immune-system activities that can cause the body to recognize a transplanted organ as foreign. By controlling this immune response, it helps protect the transplanted organ and reduce the risk of rejection. It is generally used as part of a long-term transplant treatment plan and requires regular medical monitoring.