Cenforce-100 Tablets Cenforce-100 contains Sildenafil Citrate, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). During sexual stimulation, nitric oxide (NO) is released in the corpus cavernosum, activating guanylate cyclase and increasing intracellular levels of cGMP. Sildenafil inhibits PDE5, the enzyme responsible for the breakdown of cGMP in the vascular smooth muscle of the penis, thereby facilitating the accumulation of cGMP. Elevated cGMP levels promote smooth muscle relaxation and arterial vasodilation within the erectile tissue, enhancing blood flow to the corpus cavernosum and enabling a natural erectile response. Cenforce-100 is indicated for the treatment of erectile dysfunction (ED) in adult males.