Cenforce-200 Tablets Cenforce-200 contains Sildenafil Citrate, a potent and selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). During sexual stimulation, nitric oxide (NO) is released in the corpus cavernosum, stimulating guanylate cyclase and elevating intracellular levels of cGMP. Sildenafil inhibits PDE5, preventing the enzymatic degradation of cGMP in the vascular smooth muscle of the penis and facilitating sustained cGMP accumulation. Increased cGMP levels induce smooth muscle relaxation and arterial vasodilation within the erectile tissue, enhancing blood flow to the corpus cavernosum and enabling a firm, natural erectile response. Cenforce-200 is indicated for the treatment of severe erectile dysfunction (ED) in adult males requiring a high-potency formulation.