Trombonat 50 Trombonat 50 contains Eltrombopag Olamine, an oral thrombopoietin receptor agonist that works by binding to and stimulating the TPO receptor on bone marrow progenitor cells. This signals the body to accelerate the growth and maturation of megakaryocytes, resulting in an increased production of functional blood platelets. It is prescribed to elevate platelet levels and manage bleeding risks in patients with chronic immune thrombocytopenia (ITP), severe aplastic anemia, or low platelet counts associated with Hepatitis C infection.