Oxfenda 500mg Tablets OXFENDA 500MG contains Oxfendazole, a broad-spectrum anthelmintic belonging to the benzimidazole class. Oxfendazole acts by selectively binding to parasite tubulin, inhibiting microtubule polymerization and disrupting microtubule-dependent cellular processes, such as glucose uptake and intracellular transport. This depletion of energy reserves leads to paralysis and death of susceptible parasitic helminths. OXFENDA 500MG is indicated for the control and treatment of various gastrointestinal nematode infestations, including roundworms, lungworms, and tapeworm segments.