Lamipure 150 Tablets LAMIPURE-150 contains Lamivudine (3TC), a synthetic nucleoside analogue. Intracellularly, lamivudine is phosphorylated by cellular kinases to its active metabolite, lamivudine 5'-triphosphate (3TC-TP). This active metabolite inhibits HIV reverse transcriptase and hepatitis B virus (HBV) polymerase by competing with natural deoxycytidine triphosphate (dCTP) and incorporating into nascent viral DNA, resulting in DNA chain termination due to the absence of a 3'-OH group. LAMIPURE-150 is indicated in combination with other antiretroviral agents for the treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection in adults and pediatric patients, as well as for the management of chronic hepatitis B virus infection.