Enzamide 80 Capsules Enzamide-80 contains Enzalutamide, a nonsteroidal androgen receptor inhibitor that works by blocking multiple steps in the androgen receptor signaling pathway. It competitively inhibits androgen binding to androgen receptors, inhibits nuclear translocation of activated receptors, and prevents the binding of activated androgen receptors to DNA. It is indicated for the treatment of adult men with metastatic and non-metastatic castration-resistant prostate cancer (CRPC) and metastatic castration-sensitive prostate cancer (mCSPC).