LeuGard 11.25 Depot Injection LeuGard 11.25 Depot Injection contains Leuprorelin Acetate, a gonadotropin-releasing hormone (GnRH) agonist used to manage hormone-dependent conditions. It is primarily indicated for the treatment of advanced prostate cancer and is also used in conditions such as endometriosis, uterine fibroids, central precocious puberty, and certain hormone-sensitive breast cancers. The depot formulation provides sustained drug release for up to 3 months, helping maintain effective hormone suppression with fewer injections.