NUBEQA 300 mg Tablets NUBEQA contains Darolutamide, a nonsteroidal androgen receptor antagonist. It competitively inhibits androgen binding, receptor nuclear translocation, and AR-mediated transcription, preventing the growth and proliferation of prostate cancer cells. It is indicated for the treatment of adult patients with non-metastatic castration-resistant prostate cancer (nmCRPC) and metastatic hormone-sensitive prostate cancer (mHSPC).